Correct Answer: B. Collagen VII

Explanation: Bart’s syndrome refers to congenital aplasia cutis (typically of the shins) and associated epidermolysis bullosa, most commonly dominant dystrophic EB. In dominant dystrophic EB there is a defect in Collagen VII.

Reference: Zelickson B, Matsumura K, Kist D, et al. Bart’s Syndrome Ultrastructure and Genetic Linkage. Arch Dermatol. 1995;131(6):663-668.

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