Friday Pop Quiz #252

The correct answer is E. Ultrapotent corticosteroids. 

The diagnosis of erosive pustular dermatosis is a clinical one, which is aided by the patient’s daughter describing prior pustules that have now coalesced to form this crust. While further testing for bacterial superinfection or fungal infection (eg, kerion) may be considered, ultrapotent topical corticosteroids are the mainstay of treatment for this condition, which is best performed after crusts are gently soaked and removed.

The other treatments may be considered for some of the differential diagnoses (eg, excision for squamous cell carcinoma), but these are not appropriate for the treatment of erosive pustular dermatosis.


Karanfilian KM, Wassef C. Erosive pustular dermatosis of the scalp: causes and treatments. Int J Dermatol. 2021;60(1):25-32. doi:10.1111/ijd.14955