Friday Pop Quiz #214

The correct answer is E. Neutrophils.

Recognize the pustular eruption with some scale on this newborn’s forehead as being consistent with a diagnosis of transient neonatal pustular melanosis. These lesions characteristically are a primary neutrophilic infiltrate.

Basophils, eosinophils, histiocytes, and mast cells are not the characteristic feature of the lesions of transient neonatal pustular melanosis. However, eosinophils may be occasional in this disease, though they are the primary cell type in erythema toxicum neonatorum.


Chia PS, Leung C, Hsu YL, Lo CY. An infant with transient neonatal pustular melanosis presenting as pustules. Pediatr Neonatol. 2010;51(6):356-358. doi:10.1016/S1875-9572(10)60069-1

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