Friday Pop Quiz #22

Answer: A. Lymph Nodes.

Scrofuloderma is a tuberculous or nontuberculous mycobacterial infection affecting children and young adults, representing direct extension of tuberculosis into the skin from underlying structures such as lymph nodes, bone, or lung. It most commonly presents as a neck abscess secondary to a tuberculosis infection of the cervical lymph nodes. It is manifested by the development of painless subcutaneous swellings that evolve into cold abscesses, multiple ulcers, and draining sinus tracts. The diagnosis is based on positive Mantoux test/PPD test, histologic features of caseating granulomatous inflammation, culture, and favorable response to anti-tuberculosis therapy.

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