Pop Quiz #150

The correct answer is D. Myofibroblasts.

Myofibroblasts are modified fibroblast with smooth muscle like features. Myofibroblasts play the important role in the contraction of the wound that occurs during the proliferation phase. The contraction is considered one of the important events in wound healing because it results in the closure of the wound. The correct balance between too little contraction, which leads to non-healing wounds, and too much contraction, which leads to contractures, is important for optimal healing.

The other cell types do not play a large role in wound contraction.


Chitturi RT, Balasubramaniam AM, et al. The role of myofibroblasts in wound healing, contraction and its clinical implications in cleft palate repair. J Int Oral Health. 2015 Mar;7(3):75-80. [https://www.ncbi.nlm.nih.gov/pubmed/25878485]