Friday Pop Quiz #224

The correct answer is D. Reversible corneal deposits.

This photo depicts discoid lupus, which presents with red, indurated plaques, adherent carpet tack scale, and/or atrophy and dyspigmentation. Scarring may also occur. The most common treatment for this condition is Plaquenil, which can cause reversible corneal deposits. Over time, irreversible retinopathy can occur.

Dysgeusia may occur with Hedgehog pathway inhibitors (i.e., vismodegib) used in the treatment of basal cell carcinoma and terbinafine used in the treatment of tinea/onychomycosis.

Sedation can occur with first-generation H1 antihistamines and thalidomide (used in the treatment of erythema nodosum leprosum.

Reversible motor neuropathy can occur with Dapsone.

Exuberant granulation tissue can occur with isotretinoin and EGFR inhibitors.


Koranda FC. Antimalarials. J Am Acad Dermatol. 1991;4:650-655.