Pop Quiz #65

The correct answer is B. Cowdry Type A bodies.

The concurrent presence of vesicles, pustules, erosions, and crusts is indicative of primary varicella infection. Cowdry Type A inclusion bodies are seen in HSV and VZV infection, and are characterized as large eosinophilic intranuclear inclusions with surrounding clear halos in infected cells.

Guarnieri bodies are seen in smallpox, which clinically displays lesions at the same stage of development (contrast this with the various stages of lesion development seen in varicella). Cowdry Type B inclusion bodies are seen in polio. Henderson-Patterson bodies are seen in molluscum contagiosum, and Russell bodies are found in rhinoscleroma and granuloma inguinale.

References: PMID: 1333572

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