Melanoma – Friday Pop Quiz 3/5/2021
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This 32-year-old man has two sisters each with melanoma, and his father died from metastatic pancreatic cancer. You suspect a germline mutation in which of the following genes?
A. BAP1
B. TERT
C. MITF
D. CDKN2A
E. PTCH
To find out the correct answer and read the explanation, click here.
Brought to you by our brand partner Derm In-Review. A product of SanovaWorks.
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This 32-year-old man has two sisters each with melanoma, and his father died from metastatic pancreatic cancer. You suspect a germline mutation in which of the following genes?
A. BAP1
B. TERT
C. MITF
D. CDKN2A
E. PTCH
To find out the correct answer and read the explanation, click here.
Brought to you by our brand partner Derm In-Review. A product of SanovaWorks.
… 
Histologically, this lesion shows plump, polygonal cells arranged in nests and fascicles with granular cytoplasm. Which immunohistochemical stain would be positive?
A. CD31
B. Synaptophysin
C. Factor XIIIa
D. S-100
E. CD34
To find out the correct answer and read the explanation, click here.
Brought to you by our brand partner Derm In-Review. A product of SanovaWorks.
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Which subtype of this disease is most common in the United States?
A. C
B. A
C. B
D. D
E. E
To find out the correct answer and read the explanation, click here.
Brought to you by our brand partner Derm In-Review. A product of SanovaWorks.
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The pathology of this lesion demonstrates reticulate strands of the epidermis with clefting between the strands and the stroma. What is the diagnosis?
A. Eccrine syringofibroadenoma
B. Fibroepithelioma of Pinkus
C. Squamous cell carcinoma
D. Reticulate seborrheic keratosis
E. Tumor of the follicular infundibulim
To find out the correct answer and read the explanation, click her … 
A 60-year-old patient develops a green-black to green-blue discoloration of one of her toenails. You suspect she may have green nail syndrome. Which of the following is not a predisposing factor to the development of green nail syndrome?
A. Excessive use of detergents
B. Excessive use of soaps
C. Nail trauma
D. Melanocytic nevus
E. Frequent and prolonged exposure to water
To fi … 