Spesolimab Therapeutic Cheat Sheet
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Generalized pustular psoriasis (GPP) is a rare, autoinflammatory condition, with acute, severe flares of diffuse sterile pustules and systemic symptoms that can be life-threatening. Historically, cyclosporine, methotrexate, retinoids, and biologics modulating the interleukin-17 (IL-17), IL-23, and tumor necrosis factor α pathways have been used off-label for management.1 Aberrant IL-36 signaling …
Generalized pustular psoriasis (GPP) is a rare, autoinflammatory condition, with acute, severe flares of diffuse sterile pustules and systemic symptoms that can be life-threatening. Historically, cyclosporine, methotrexate, retinoids, and biologics modulating the interleukin-17 (IL-17), IL-23, and tumor necrosis factor α pathways have been used off-label for management.1 Aberrant IL-36 signaling … 
A laboratory’s recent claim that it detected the carcinogen benzene in certain acne treatments made news recently. The lab, Valisure, filed a petition with the FDA asking for a recall of the products involved. Chemists quoted in an Allure article said the issue is not one of contamination but potentially one of decomposition. The lab says it detected benzene when the benzoyl peroxide products we … 
Dr. Adam Friedman's lecture at 2024 ODAC conference provided invaluable insights into the nuanced approach required when dealing with patients presenting with alopecia. Addressing the diverse array of alopecia types and their myriad presentations, Dr. Friedman emphasized the significance of a comprehensive clinical history and evaluation to formulate an effective treatment plan. By employing a cas … 
The latest buzz word in hidradenitis suppurativa treatment is combination. Without a single, consistently and widely effective therapy, it’s important to build your own regimen by combining treatments, says Dr. Steven Daveluy, associate professor of dermatology and residency program director at Wayne State University School of Medicine. Next Steps in Derm, in partnership with ODAC Dermatology, A … 
ABSTRACT
Post-hyaluronic acid filler nodules are uncommon, unpredictable complications that present a challenge to clinical therapy. JDD authors Miyahra Haniko P. Lopez MD MBA, Sophie H. Guenin MSc, Jennifer Laborada BS, and Mark G. Lebwohl MD report a case of a female in her fifties who developed edema and nodules 6 weeks after hyaluronic acid (HA) filler injection. After minimal improvement wit … 