Improvement of Pretibial Myxedema Following Administration of Teprotumumab
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Pretibial myxedema (PTM) is a rare complication of Graves' disease. It is characterized by non-pitting edema with hyperpigmented hyperkeratotic papules and plaques on bilateral lower legs. Effective treatments for patients with PTM are lacking. The etiology of PTM is unknown; however, it may be similar to the mechanism of thyroid-associated ophthalmopathy (TAO). Activated fibroblasts produce infla …
Pretibial myxedema (PTM) is a rare complication of Graves' disease. It is characterized by non-pitting edema with hyperpigmented hyperkeratotic papules and plaques on bilateral lower legs. Effective treatments for patients with PTM are lacking. The etiology of PTM is unknown; however, it may be similar to the mechanism of thyroid-associated ophthalmopathy (TAO). Activated fibroblasts produce infla … Continue reading "Improvement of Pretibial Myxedema Following Administration of Teprotumumab"
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A 2 day-old infant is being seen in the hospital for the following rash. Which of the following is not true about the infant’s disease?
A. Skin lesions typically resolve without scarring
B. There is a strong association with anti-SSA/Ro antibodies
C. There are also reports of the presence of U1RNP antibodies
D. Lesions have a predilection for the face
E. Heart block often deve … 