Spesolimab Therapeutic Cheat Sheet
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Generalized pustular psoriasis (GPP) is a rare, autoinflammatory condition, with acute, severe flares of diffuse sterile pustules and systemic symptoms that can be life-threatening. Historically, cyclosporine, methotrexate, retinoids, and biologics modulating the interleukin-17 (IL-17), IL-23, and tumor necrosis factor α pathways have been used off-label for management.1 Aberrant IL-36 signaling …
Generalized pustular psoriasis (GPP) is a rare, autoinflammatory condition, with acute, severe flares of diffuse sterile pustules and systemic symptoms that can be life-threatening. Historically, cyclosporine, methotrexate, retinoids, and biologics modulating the interleukin-17 (IL-17), IL-23, and tumor necrosis factor α pathways have been used off-label for management.1 Aberrant IL-36 signaling … 
Pediatric dermatologic emergencies are very real, highlights Dr. Kalyani Marathe, Associate Professor of Dermatology and Pediatrics at the University of Cincinnati, who lectured during ODAC 2023. Pediatric dermatologic emergencies represent almost 4% of emergency room visits, and of those, most are related to chronic skin disease, drug eruptions, and infections. Here, we will review some of those … 
Before we dive into our discussion, let’s outline the Guideline-Based Approach to Treatment Selection.
The International Psoriasis Council has divided psoriasis treatment classification into 2 groups:
Patients who are a candidate for topical therapy, or
Patients who are a candidate for systemic therapy
Candidates for systemic therapy must meet at least 1 of the following … 
During the recent DERM2O22 NP/PA CME conference held July 28-31, 2022, Drs. David Cohen, Brad Glick, and Adam Friedman led a case-based panel discussion on atopic dermatitis (AD) treatment initiation and monitoring. This article provides a summary of their discussion and recommendations.
CASE 1
51-year-old male with a 20-year history of AD. The patient was first seen in September 2015 with BSA … 
Did you know that psoriasis doesn’t just present on the arms, legs, and trunk? It can also appear in non-conventional locations (aka “special site” psoriasis) including the scalp, face, and body folds (such as the axillary, inframammary, and inguinal fields, and intergluteal clefts). In the skin folds, psoriasis is also referred to as “inverse psoriasis.” In darker skin types, the areas … 