DUPILUMAB

From Port-Wine Stain Treatments to Bovine Colostrum, Telomeres, and Skin Aging
130701307013070Port-Wine StainThe May issue of the Journal of Drugs in Dermatology features dermatology articles on topics ranging from treatment updates on Port-Wine stain to the protective effect that liposomal bovine colostrum exerts on skin aging using telomere length as an aging biomarker. Straight from the JDD Editor’s desk, we share this month’s issue highlights: Authors analyze extrusion forces of various produ …
Port-Wine Stain
Recalcitrant Dyshidrotic Eczema Treated With Dupilumab
129441294412944eczemaThe following two cases presented by JDD authors Ryan A. Gall MD, John D. Peters MD, and Alyson J. Brinker MD add to the growing literature supporting the use of dupilumab in the treatment of patients with recalcitrant dyshidrotic eczema, both with and without diagnosed contact allergens. Introduction Dyshidrotic eczema, also known as dyshidrosis or pompholyx when involving larger bullae, is a c …
eczema
Novel Therapeutics in Atopic Dermatitis
127381273812738Novel Therapies Atopic DermatitisAtopic dermatitis (AD) is a chronic inflammatory skin disease. The pathogenesis of AD is complex with many mediators involved and can be broken down into 4 categories: Immune dysregulation Abnormal skin barrier Abnormal itch/scratch cycle Abnormal skin microbiome In AD, there is a breakdown in molecular control of the immune system, leading to overproduction and expressi …
Novel Therapies Atopic Dermatitis
Dupilumab Therapeutic Cheat Sheet
124141241412414DupilumabAtopic dermatitis (AD) is a common skin condition characterized by pruritus and occurs as a result of factors related to impaired skin barrier and immune response, as well as environmental and infectious agents. Patients with poor control on topical therapy are looking for safe and effective systemic treatments. We continue our series, Therapeutic Cheat Sheet, with a closer look at dupilumab, whic …
Dupilumab
Beyond the Basics: Systemic Treatment for Atopic Dermatitis and Evaluation of Infantile Hemangiomas
123821238212382Infantile Hemangiomas To kick off ODAC 2021, Dr. Yasmine Kirkorian, MD, tackled two clinical dilemmas that are frequently seen among pediatric patients in the dermatology office: poorly controlled atopic dermatitis and infantile hemangiomas. Dr. Kirkorian reviewed currently available systemic therapies for atopic dermatitis as well those in the drug development pipeline. She went into detail about how she utilizes he …
Infantile Hemangiomas