hyperkeratosis

Peripheral Arthritis – Friday Pop Quiz 10/27
182551825518255 A 28-year-old previously healthy man presents with thick crusting and hyperkeratosis of the palms and soles, urethritis, and one month of peripheral arthritis. Which of the following is true regarding his condition? A. Females and males are equally affected B. About 20% of patients will have a long-term disease that results in enthesitis and destructive arthritis. C. TNF-alpha inhibit …
Verrucous Psoriasis: Rare Variant and Novel Treatment
180401804018040Verrucous PsoriasisJDD authors Dimitra Xenopoulou MS, Christopher Pochat MS, and Evelyn Greco DO present the findings of a successful treatment for verrucous psoriasis.  CASE A 64-year-old female presented to the outpatient clinic for the evaluation of flaking and itchy lesions on her bilateral hands and feet that were present for several months and caused difficulty with activities of daily living. Inconsist …
Verrucous Psoriasis
Hand Foot Skin Reaction Associated With Palbociclib
133961339613396PalbociclibINTRODUCTION Palbociclib is one of three new small-molecule inhibitors of cyclin-dependent kinase 4 and 6 (CDK4/6) approved for use in the treatment of hormone receptor positive (HR+) and human epidermal growth factor receptor 2 negative (Her2-) advanced or metastatic breast cancer. CDK4/6 inhibitors have a good overall safety profile but reported side effects include cytopenias, diarrhea, QTc pr …
Palbociclib
Alopecia in Skin of Color: Alternative Therapies
121411214112141Alopecia in Skin of ColorManagement of alopecia in skin of color is challenging due to a paucity of research into its pathophysiology coupled with a poor understanding of the basic hair care practices in this patient population. For the patient, it is often associated with severe emotional distress. Unfortunately, many forms of hair loss are refractory to standard therapies. At the 2020 Skin of Color Virtual Update, Dr …
Alopecia in Skin of Color