Gut-Immune-Skin Axis: What Happens in the Gut Matters to the Skin
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The gut-immune-skin axis describes how the gut microbiome communicates with the skin via complex interactions with the immune system to regulate local and systemic inflammation. Before attempting to delineate that relationship, we must first grasp a firm understanding of the gut ecosystem. The gut ecosystem is made up of the epithelial interface, which is characterized by
the epithelial …
The gut-immune-skin axis describes how the gut microbiome communicates with the skin via complex interactions with the immune system to regulate local and systemic inflammation. Before attempting to delineate that relationship, we must first grasp a firm understanding of the gut ecosystem. The gut ecosystem is made up of the epithelial interface, which is characterized by
the epithelial … Continue reading "Gut-Immune-Skin Axis: What Happens in the Gut Matters to the Skin"
Atopic dermatitis (AD) is a chronic inflammatory skin disease. The pathogenesis of AD is complex with many mediators involved and can be broken down into 4 categories:
Immune dysregulation
Abnormal skin barrier
Abnormal itch/scratch cycle
Abnormal skin microbiome
In AD, there is a breakdown in molecular control of the immune system, leading to overproduction and expressi … 