Alitretinoin Therapeutic Cheat Sheet
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Alitretinoin (9-cis-retinoic acid) is a naturally occurring endogenous retinoid that in gel form is FDA approved for AIDs-related localized cutaneous Kaposi’s sarcoma (KS)1. As compared to other topical retinoids, alitretinoin is unique in that it binds to all known intracellular retinoid receptors (RARs and RXRs), allowing it to exert anti-proliferative and apoptotic effects, particularly usefu …
Alitretinoin (9-cis-retinoic acid) is a naturally occurring endogenous retinoid that in gel form is FDA approved for AIDs-related localized cutaneous Kaposi’s sarcoma (KS)1. As compared to other topical retinoids, alitretinoin is unique in that it binds to all known intracellular retinoid receptors (RARs and RXRs), allowing it to exert anti-proliferative and apoptotic effects, particularly usefu … 
Dr. Eliot Battle, co-chair of the Skin of Color Update conference and CEO/Founder of Cultura Dermatology & Plastic Surgery, has a distinguished history of establishing safe and effective laser techniques in patients with skin of color. During his recent lecture at the 2023 Skin of Color Update conference, he shared with the audience his personal pearls and suggestions for establishing a thrivi … 
Hidradenitis Suppurativa (HS) is a challenging dermatological condition characterized by painful, recurrent, and often disfiguring skin lesions. In this article, we will explore the expert insights of Dr. Ginette Okoye, Professor and Chair of the Howard University Department of Dermatology, as she discussed her approach to and experience with treating patients with HS at the 2023 Skin of Color Upd … 
INTRODUCTION
Benign Familial Pemphigus, or Hailey-Hailey Disease (HHD), affects intertriginous areas of the skin causing epidermal blistering and vesicles that coalesce into weeping and crusting plaques.¹
The loss-of-function mutation of the ATP2C1 gene causes a disruption in calcium homeostasis of keratinocytes. The resulting dysfunction in desmosomes and cell-cell adhesion causes acanthol … 
Current field-directed treatments of actinic keratosis (AK), a pre-malignant condition, are often limited by severe local reactions and/or complex treatment. Tirbanibulin, a novel potent anti-proliferative synthetic agent that inhibits tubulin polymerization and Src kinase signalling, offers a convenient, safe, and effective field treatment of actinic keratosis. We continue our surgical Therapeut … 