This 34-year-old woman reports a long history of Raynaud’s phenomenon. The only medication she takes is albuterol as needed for exercise-induced asthma. On exam, you notice splinter hemorrhages of the fingernails as well as the pictured findings. Which of the following antibodies is LEAST likely to be positive in this woman?

A. Anti-nuclear

B. Anti-histone

C. Anti-B2 glycoprotein

D. Lupus anticoagulant

E. Anti-cardiolipin

To find out the correct answer and read the explanation, click here. 

Brought to you by our brand partner Derm In-Review.  A product of SanovaWorks.