JDD Corner

JDD April 2024 Issue Highlights

Introducing the April 2024 Editorial Highlights from the Journal of Drugs in Dermatology! This month’s issue is packed with groundbreaking research and insights into dermatologic treatments and practices. From original articles exploring innovative therapies for conditions like photoaging and acne vulgaris to case reports shedding light on rare dermatologic phenomena, this issue offers a comprehensive view of the latest advancements in dermatology. Join us as we delve into the efficacy of topical treatments, novel approaches to skincare, and the impact of emerging therapies on patient outcomes. Straight from the editor’s desk, we share this month’s issue highlights.

Original Articles

Efficacy and Tolerability of Topical 0.1% Stabilized Bioactive Retinol for Photoaging: A Vehicle-Controlled Integrated Analysis provides new evidence for improving signs of photoaging without causing major irritation.

Treatments for Moderate-to-Severe Acne Vulgaris: A Systematic Review and Network Meta-Analysis suggests that topical triple-agent FDC gel was the most efficacious and safe treatment for moderate-to-severe acne.

A Practical Algorithm Integrating Skin Care With Nonenergy and Injectable Dermatologic Procedures to Improve Patient Outcomes and Satisfaction presents a consensus on an algorithm for supportive skin care for nonenergy and injectable anti-aging treatments.

A Silymarin Antioxidant Serum Improves Facial Acne Alone and as Part of a Treatment Regimen presents a regimen for improving facial appearance in blemish-prone skin.

Human Clinical Trials Using Topical Bakuchiol Formulations for the Treatment of Skin Disorders: A Systematic Review looks into human clinical trials using topical formulations containing bakuchiol in the treatment of facial skin disorders.

COVID-19 Protection Strategies: Lessons Learned About Epidermal Barrier Function and the Significance of Optimized Skin Care explores conditions affecting healthcare workers.

Comparing the Safety and Effectiveness of Microfocused Ultrasound: Standard Versus Targeted Tissue Protocol in Lifting and Tightening the Lower Face and Upper Neck emphasizes the importance of visualization with ultrasound to confirm all coagulation points are delivered

The Effectiveness and Safety of a New Hyaluronic Acid Injectable for Augmentation and Correction of Chin Retrusion aims to demonstrate the superiority of HASHA vs no-treatment.

The Two-Stage Folded Paramedian Forehead Flap Without Cartilage Grafts for Full Thickness Distal Nasal Defects: A Review of 35 Patients explores a dependable and efficient option for repairing full-thickness unilateral defects of the nose.

Aesthetic Improvement With Topical Body Skin Treatment as a Complement to Cryolipolysis suggests that FTB may complement skin improvements seen post-NIBC.


Cutaneous Squamous Cell Carcinoma In Situ on a Fingernail Treated With HPV Vaccine adds to the growing body of evidence that the 9-valent HPV vaccine may be well-tolerated and effective.

The Koebner Phenomenon in Bullous Pemphigoid reports on a case of peristomal BP that emerged after a colostomy.

Mitogen-Activated Protein Kinase Inhibitor-Induced Inflammatory Alopecia in Woman With Ovarian Cancer shares the first reported case of inflammatory alopecia.

Oral Lichen Planus Successfully Treated With Upadacitinib shares a promising treatment option in difficult dermatologic conditions including OLP.


Dermatologists’ Perspectives on Biosimilars shares the results of a 27-question survey from 52 medical professionals.

Topical Human Mesenchymal Stem Cell-Derived Exosomes for Acceleration of Wound Healing Following Tissue Trauma and Aesthetic Procedures: A Case Series illustrates the potential for exosomes to be a versatile and important part of clinical care.

Molecular Insights Into the Effects Of PLLA-SCA on Gene Expression and Collagen Synthesis in Human 3D Skin Models Containing Macrophages aims to investigate the molecular effects of PLLA-SCA in a comprehensive in vitro study.

Functional and Cutaneous Treatment Outcomes With Intravenous Immunoglobulin for Eosinophilic Fasciitis: A Retrospective Study aims to describe the functional and cutaneous outcomes associated with IVIG in adults with treatment-refractory EF at a tertiary referral center.

Expanding Inclusivity: Tranexamic Acid for the Treatment of Melasma in Males shares the success in treating many melasma patients.


Analysis of Utilization, Cost, and Prescription Trends of Common Immunosuppressive Medications Among Medicare Patients 2013 to 2019 finds an overall increase in total claims for non-biologic immunosuppressive therapies.

Clinical Impacts of Omalizumab on the Psychiatric Comorbidities of Chronic Spontaneous Urticaria: A Systematic Review and Meta-Analysis further support the use of omalizumab in the management of moderate-to-severe CSU.

Expression of IL-4 in Tumors: A Safety Surrogate to Predict Cancer Survival Associated With Biologic Therapies supports that dupilumab is unlikely to be associated with an increased malignancy risk.

Advancing Dermatology Education and Care in Rwanda: The Impact of a New Academic Partnership shares the current state of creating an academic institution dedicated to health equity.

Analysis of Reddit Reveals JAK Inhibitor Questions Among Atopic Dermatitis Patients finds many gaps in patient knowledge, showing areas for future improvement.


Antihyperglycemic Medication to Combat Skin AGE-ing suggests that studies on the effects of GLP-1 RAs and their impact on skin aging specifically are necessary.

Find more JDD Issue Highlights here