Improvement of Pretibial Myxedema Following Administration of Teprotumumab
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Pretibial myxedema (PTM) is a rare complication of Graves' disease. It is characterized by non-pitting edema with hyperpigmented hyperkeratotic papules and plaques on bilateral lower legs. Effective treatments for patients with PTM are lacking. The etiology of PTM is unknown; however, it may be similar to the mechanism of thyroid-associated ophthalmopathy (TAO). Activated fibroblasts produce infla …
Pretibial myxedema (PTM) is a rare complication of Graves' disease. It is characterized by non-pitting edema with hyperpigmented hyperkeratotic papules and plaques on bilateral lower legs. Effective treatments for patients with PTM are lacking. The etiology of PTM is unknown; however, it may be similar to the mechanism of thyroid-associated ophthalmopathy (TAO). Activated fibroblasts produce infla … Continue reading "Improvement of Pretibial Myxedema Following Administration of Teprotumumab"
A 62-year old patient was admitted for new-onset shortness of breath secondary to pneumonia. Dermatology was consulted to evaluate a pruritic skin eruption affecting multiple body sites. She denied prior skin problems, and antihistamines failed to improve the it … 
Which of the following is least likely to be associated with the condition depicted in the image?
A. Insulin-dependent diabetes
B. Pernicious anemia
C. Pseudotumor cerebri
D. Hashimoto's thyroiditis
E. Grave's disease
To find out the correct answer and read the explanation, click here.
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