Tinea versicolor – Friday Pop Quiz 9/2/2022

A 42-year-old male presents with multiple round to oval hypomelanotic patches measuring several centimeters in size. The lesions coalesce centrally and are more prominent on the trunk. Associated fine scale is apparent upon scratching the skin. The distribution is symmetric and favors the chest, abdomen, and back. Which of the following is not a proposed mechanism of the hypopigmented skin in tinea versicolor?

A. Azelaic acid inhibits tyrosinase produced by Malassezia furfur

B. Abnormal melanosome production

C. Decreased melanin synthesis

D. Partial block in melanosome transfer to keratinocytes

E. Kojic acid plays a role in decreased melanin synthesis

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