JDD Corner

JDD February 2024 Issue Highlights

Explore the February 2024 issue of the Journal of Drugs in Dermatology! Discover groundbreaking research on topics such as novel treatments for melasma, advancements in psoriasis management, gene expression profile (GEP) testing for squamous cell carcinoma, pediatric vitiligo, and many more! Stay ahead of the curve with the latest insights from leading dermatology experts. Straight from the Editor’s desk, we share this month’s issue highlights!


Cysteamine Isobionic-Amide Complex Versus Kligman’s Formula for the Treatment of Melasma: Equal Efficacy and Rapid Onset of Action aims at investigating the efficacy and tolerability of cysteamine isobionic-amide complex in comparison to those of mKF for the treatment of melasma. 

Outcomes for Psoriasis by Self-Identified Racial Groups in Ixekizumab Clinical Trials: A Pooled Analysis evaluates treatment response to ixekizumab in patients with psoriasis across different self-identified racial subgroups.

Targeting the Aryl Hydrocarbon Receptor to Address the Challenges of Atopic Dermatitis discusses the rationale for targeting AhR in the treatment of AD based on the current understanding of the role of tapinarof in the treatment of inflammatory skin disease. 

Perceptions, Utilization, and Cost Assessment of Sebaceous Hyperplasia Treatment Modalities: A Pilot Survey aims to evaluate treatment approaches and their respective costs from over 220 dermatologists.

The benefit of Topical Combination Therapy for Acne: Analyzing Effect Size Using Number Needed to Treat discusses how topical acne trials face challenges in comparing treatments.

Halobetasol Propionate 0.01% and Tazarotene 0.045% Lotion With a Ceramide-Containing Moisturizer in Adults With Psoriasis evaluates the clinical profile of HP/TAZ applied before versus after a ceramide-containing moisturizer in adults with mild-to-moderate plaque psoriasis.

Incorporating a Prognostic Gene Expression Profile Test Into the Management of Cutaneous Squamous Cell Carcinoma: An Expert Consensus Panel Report reviews the available literature on the use of gene expression profile (GEP) testing to assess prognosis in cSCC and create consensus statements to guide dermatology clinicians on its use

Improvement of Chronic Venous Insufficiency Related Leg Xerosis and Dermatitis With Ceramide-Containing Cleansers and Moisturizers: An Expert-Based Consensus explores skin barrier restoration using skincare for xerosis and VLD.

Deucravacitinib for Moderate-to-Severe Psoriasis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials suggests that deucravacitinib is an effective treatment option for moderate-to severe psoriasis, with a favorable safety profile up to 16 weeks of treatment. 

Blood Monocyte Count Can Predict Early Response to Secukinumab Therapy in Patients With Psoriasis demonstrates that lower baseline blood monocyte counts may be associated with early response to treatment with secukinumab. 

The Gastrointestinal Microbiome and Immune Checkpoint Inhibitors: A Review of Human Interventional Studies Among Melanoma Patients seeks to assess the effect of microbiota-modulatory interventions on the clinical and immunological response of metastatic melanoma treated with ICIs.

Sensitive Skin: A Survey of Dermatology Resident Physicians’ Perspectives and Educational Exposures seeks to determine dermatology resident physicians’ exposure to education about SS, perspectives on SS, and management approaches.

New Insights Into Systemic Drivers of Inflammation and Their Contributions to the Pathophysiology of Acne conceptualizes beyond just the correlation of how individual medications modify pathways of AV lesion formation.


Atopic Dermatitis as a Paradoxical Reaction to Secukinumab in a Patient With Plaque Psoriasis highlights a severe paradoxical reaction to secukinumab, necessitating systemic intervention for adequate control.

Sarecycline as a Potential Treatment for Steroid-Induced Rosacea/Perioral Dermatitis: A Case Report demonstrates effective therapy for patients with SIR by sarecycline, a third-generation tetracycline antibiotic. 

Neoadjuvant PD-1 Inhibitors: A Tale of Two Cases demonstrates the real-world efficacy of neoadjuvant use of PD-1 inhibitors in the setting of advanced resectable MCC and SCC.

Atypical Dyschromia in Skin of Color presents 3 cases of atypical dyschromia in skin of color to highlight the underlying hypo- and depigmentation that may present with active disease and persist despite appropriate treatment.

A Case Series of TNF-Inhibitor Induced Psoriasis Successfully Treated With Upadacitinib reports on three patients with TNF-i-induced psoriasis who were treated with upadacitinib and experienced complete resolution of their psoriatic eruption.

Psoriasis and Palmoplantar Pustulosis Following Pembrolizumab Therapy Successfully Treated With Topical Tapinarof Cream 1% discusses how tapinarof topical monotherapy may be a useful treatment for ICI-related psoriasis and PPP.


A New Tool to Improve Communication Between Hidradenitis Suppurativa Patients and Health Care Providers characterizes significant HS historical information about a diverse patient population seeking care from a renowned HS specialist at a tertiary care center. 

Number of Affected Nails Is the Primary Determinant of Efinaconazole 10% Solution Usage for Onychomycosis shares the results of their hypothesis.   


Teledermatology Platforms Usage and Barriers: A Cross-Sectional Analysis of US-Based Dermatologists Pre- and Post-COVID-19 identifies the differences in teledermatology platform usage and functionality among dermatologists as a means of understanding the potential effect on virtual healthcare access.

Tips, Trends, and Truths: A Study of Psoriasis Treatment Content on TikTok compares the viewer engagement, content quality, and viewer experience of psoriasis treatment TikTok videos between physicians and non-physicians.

Topical Calcineurin Inhibitors in the Management of Chronic Pruritus in Older Adults: A Research Letter aims to analyze the literature to date on the utilization of topical calcineurin inhibitors in the management of pruritus among older adults, ages 65 and older.

Implicit Bias and Clinical Decision Making in Psoriasis Management Among Dermatology Residents: A Feasibility Study demonstrates no statistically significant difference in dermatology residents’ management of severe psoriasis between two different skin types.

The Pediatric Dermatologist’s View of Pediatric Vitiligo identifies practice patterns of pediatric dermatologists treating vitiligo.


What’s Old Is New: An Emerging Focus on Dermatoporosis discusses the promising use of VD analogs to treat dermatoporosis.

Find more JDD Issue Highlights here